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	Provedor de dados BJMBR (1) Genet. Mol. Biol. (1) Autor Alencar,M.A. (1) Arantes,P.M.M. (1) Dias,J.M.D. (1) Dias,R.C. (1) Fernández-Torres,Javier (1) Garrido-Rodríguez,Daniela (1) Kirkwood,R.N. (1) Lozada,Carlos (1) Martínez-Flores,Karina (1) Martínez-Nava,Gabriela Angélica (1) Pereira,L.S.M. (1) Zamudio-Cuevas,Yessica (1) Mais... Palavra-chave Knee osteoarthritis (2) Elderly women (1) Epistasis (1) Extracellular matrix (1) Falls (1) Functional performance (1) Multifactor dimensionality reduction (1) Muscular function (1) Polymorphisms (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2020 (1) 2007 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Epistasis of polymorphisms related to the articular cartilage extracellular matrix in knee osteoarthritis: Analysis-based multifactor dimensionality reduction Genet. Mol. Biol. Fernández-Torres,Javier; Martínez-Nava,Gabriela Angélica; Zamudio-Cuevas,Yessica; Lozada,Carlos; Garrido-Rodríguez,Daniela; Martínez-Flores,Karina. Abstract Osteoarthritis (OA) is a complex disease with a multifactorial etiology. The genetic component is one of the main associated factors, resulting from interactions between genes and environmental factors. The aim of this study was to identify gene-gene interactions (epistasis) of the articular cartilage extracellular matrix (ECM) in knee OA. Ninety-two knee OA patients and 147 healthy individuals were included. Participants were genotyped in order to evaluate nine variants of eight genes associated with ECM metabolism using the OpenArray technology. Epistasis was analyzed using the multifactor dimensionality reduction (MDR) method. The MDR analysis showed significant gene-gene interactions between MMP3 (rs679620) and COL3A1 (rs1800255), and between... Tipo: Info:eu-repo/semantics/article Palavras-chave: Epistasis; Extracellular matrix; Knee osteoarthritis; Multifactor dimensionality reduction; Polymorphisms. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000400102 Muscular function and functional mobility of faller and non-faller elderly women with osteoarthritis of the knee BJMBR Alencar,M.A.; Arantes,P.M.M.; Dias,J.M.D.; Kirkwood,R.N.; Pereira,L.S.M.; Dias,R.C.. Falls are a major concern in the elderly population with chronic joint disease. To compare muscular function and functional mobility among older women with knee osteoarthritis with and without a history of falls, 15 elderly women with a history of falls (74.20 ± 4.46 years) and 15 without a history of falls (71.73 ± 4.73 years) were studied. Muscular function, at the angular speed of 60, 120, and 180º/s, was evaluated using the Biodex Isokinetic Dynamometer. The sit-to-stand task was performed using the Balance Master System and the Timed Up and Go test was used to determine functional mobility. After collection of these data, the history of falls was investigated. A statistically significant difference was detected in the time taken to transfer the center... Tipo: Info:eu-repo/semantics/article Palavras-chave: Elderly women; Falls; Knee osteoarthritis; Muscular function; Functional performance. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200016 Registros recuperados: 2 Primeira ... 1 ... Última

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